EPA from Fish Oil Most Critical in Depression

by Dr. Laura Brown
on 15 November 2016
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™Fish Oil supplementation is useful in the treatment of mood disorders. Getting the right balance and the right dose is critical to the most effective treatment. 
EPA content (as opposed to DHA) most critical for fish oil to work in  both depression and major depressive disorder.
Average dose of EPA+DHA was 1.39 g (range 0.63–6.2 of EPA and 0.27–3.4 of DHA)
™1.93 g (range 1–6) pure EPA
™0.86 g (range 0.22–2) pure DHA


Ref: Grosso G, Pajak A, Marventano S, et al. Role of Omega-3 Fatty Acids in the Treatment of Depressive Disorders: A Comprehensive Meta-Analysis of Randomized Clinical Trials. Malaga G, ed. PLoS ONE. 2014;9(5):e96905. doi:10.1371/journal.pone.0096905.